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1460 CE
1470 CE
1480 CE
1490 CE
1500 CE
1510 CE
1520 CE
1530 CE
1540 CE
1550 CE
1560 CE
1570 CE
1580 CE
1465 CE - 1524 CE: Life of the conquistador Diego Velázquez de Cuéllar who conquered and then governed Cuba.
1475 CE - 1538 CE: Life of the Spanish conquistador Diego de Almagro.
1478 CE - 1541 CE: Life of the Spanish conquistador Francisco Pizarro.
1485 CE - 1541 CE: Life of the Spanish conquistador Pedro de Alvarado.
1485 CE - 1547 CE: Life of the Spanish conquistador Hernán Cortés.
1489 CE - 1527 CE: Life of the conquistador Juan de Grijalva.
1492 CE - 1580 CE: Life of the Spanish conquistador and chronicler Bernal Díaz.
1500 CE - 1542 CE: Life of the Spanish conquistador Hernando de Soto.
1511 CE - 1513 CE: Diego Velázquez de Cuéllar conducts the Spanish conquest of Cuba.
1513 CE: The notary Rodrigo de Colmemares reads out the Spanish Requirement for the first time to indigenous people in Colombia.
1517 CE: Diego Velázquez de Cuéllar sends an expedition led by Francisco Hernández de Córdoba to explore the Yucatán peninsula.
1518 CE: Diego Velázquez de Cuéllar sends an expedition led by Juan de Grijalva to explore the Yucatán peninsula.
1518 CE: Juan de Grijalva leads an expedition to explore the eastern coast of Mexico.
1519 CE: Diego Velázquez de Cuéllar sends an expedition led by Hernán Cortés to explore the Yucatán peninsula.
1519 CE - 1521 CE: Diego Velázquez de Cuéllar and Hernán Cortés contest who has the legal right to lead the conquest of Mexico.
1520 CE: Hernán Cortés is obliged to leave Tenochtitlan and face a rival force of conquistadors led by Panfilo de Narváez at Veracruz.
1520 CE: The bloody retreat of Hernán Cortés from Tenochtitlan known as the Noche Triste ('Sad Night').
1520 CE: Hernán Cortés defeats a large Aztec army at Otumba.
1520 CE: Hernán Cortés captures the city of Texcoco.
1521 CE: The Aztec capital of Tenochtitlan falls into the hands of Spanish forces led by Hernán Cortés.
1522 CE: Hernán Cortés leads an expedition against the Huaxtecs in Mexico.
1523 CE - 1524 CE: Hernán Cortés organises an expedition to Honduras led by Cristóbal de Olid.
1523 CE - 1524 CE: The conquistador Pedro de Alvarado leads the conquest of the Maya in Guatemala.
1523 CE: Hernán Cortés is appointed the first governor of the colony of New Spain (Mexico).
1525 CE - 1528 CE: The conquistador Pedro de Alvarado leads the conquest of El Salvador.
1525 CE: Juan de Grijalva leads the naval part of a Spanish expedition to explore northern Mexico.
1527 CE: Pedro de Alvarado is offically made the governor of Guatamala.
1527 CE: The Spanish conquistador Juan de Grijalva is killed in Honduras.
1528 CE: Hernán Cortés returns to Spain and is honoured by Charles V, Holy Roman Emperor.
1531 CE - 1532 CE: Hernán Cortés explores the Pacific coast of North America as far as California.
1532 CE: Francsico Pizarro and the Spanish conquistadors arrive in South America.
1532 CE: Hernando de Soto reads out the Spanish Requirement to the Inca ruler Atahualpa.
1534 CE: Pedro de Alvarado leads an expedition of conquistadors to Ecuador and Peru.
1535 CE: Diego de Almagro leads a 20-month long expedition to explore Chile.
1537 CE: Hernando de Soto is made a Knight of Santiago, the governor of Cuba, and awarded the status of adelantado for North American exploration.
1538 CE: The Spanish conquistador Pedro de Alvarado is made the governor of Honduras.
1539 CE - 1542 CE: The spanish conquistador Hernando de Soto leads an expedition of discovery and conquest in Florida and the southwestern part North America.
1540 CE: Pedro de Alvarado joins an expedition led by Francisco Vásquez de Coronado to explore North America.