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400 CE
410 CE
420 CE
430 CE
440 CE
450 CE
460 CE
470 CE
401 CE: Birth of Byzantine emperor Leo I.
457 CE - 474 CE: Reign of Byzantine emperor Leo I.
457 CE: Leo I is crowned by the Patriarch of Constantinople, the first Byzantine emperor to be crowned by a bishop.
466 CE: Byzantine emperor Leo I gives his daughter Ariadne as a wife to the Isaurian chief Tarasicodissa (Zeno).
468 CE: A Byzantine army led by Basiliscus is defeated by the Vandals in North Africa.
471 CE: Byzantine emperor Leo I conspires to murder his rival the general Aspar.
474 CE: Byzantine emperor Leo I dies of dysentery.